Savave Kiwof Plus (Dog Dewormer- Chewable Tablets)
COMPOSITION:
Each chewable tablet contains:
Praziquantel IP                    50 mg
Pyrantel Pannoate IP          144 mg
Febantel                                150 mg 
Excipients                            q.s.
PHARMACOLOGY
Kiwof - Plus Tablets contain three active ingredients having different modes of action and spectra of activity. Praziquantel is active against cestodes (tapeworms). Praziquantel is absorbed, metabolized in the liver and excreted in the bile. Upon entering the digestive tract from the bile, cestocidal activity is exhibited. Following exposure to praziquantel, the tapeworm loses its ability to resist digestion by the mammalian host. Because of this, whole tapeworms, including the scolices, are very rarely passed after administration of praziquantel. In many instances only disintegrated and partially digested pieces of tapeworms will be seen in the stool. The majorities of tapeworms are digested and are not found in the feces.
Pyrantel pamoate is active against hookworms and ascarids. Pyrantel pamoate acts on the cholinergic receptors of the nematode resulting in spastic paralysis. Peristaltic action of the intestinal tract then eliminates the parasite.
Febantel is active against nematode parasites including whipwornns. Febantel is rapidly absorbed and metabolized in the animal.
Available information suggests that the parasite's energy metabolism is blocked, leading to energy exchange breakdown and inhibited glucose uptake.